2XC8

Crystal structure of the gene 22 product of the Bacillus subtilis SPP1 phage

2XC8 の概要

• エントリーDOI: 10.2210/pdb2xc8/pdb
• 分子名称: GENE 22 PRODUCT (2 entities in total)
• 機能のキーワード: siphoviridae, gram-positive phage, viral protein
• 由来する生物種: BACILLUS PHAGE SPP1
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 50472.88

構造登録者

Veesler, D.,Blangy, S.,Tavares, P.,Campanacci, V.,Cambillau, C. (登録日: 2010-04-19, 公開日: 2010-06-09, 最終更新日: 2024-11-13)

主引用文献

Veesler, D.,Blangy, S.,Spinelli, S.,Tavares, P.,Campanacci, V.,Cambillau, C.
Crystal Structure of Bacillus Subtilis Spp1 Phage Gp22 Shares Fold Similarity with a Domain of Lactococcal Phage P2 Rbp.
Protein Sci., 19:1439-, 2010

PubMed Abstract: SPP1 is a siphophage infecting the gram-positive bacterium Bacillus subtilis. It is constituted by an icosahedric head and a long non-contractile tail formed by gene products (gp) 17-21. A group of 5 small genes (gp 22-24.1) follows in the genome those coding for the main tail components. However, the belonging of the corresponding gp to the tail or to other parts of the phage is not documented. Among these, gp22 lacks sequence identity to any known protein. We report here the gp22 structure solved by X-ray crystallography at 2.35 A resolution. We found that gp22 is a monomer in solution and possesses a significant structural similarity with lactococcal phage p2 ORF 18 N-terminal "shoulder" domain.

PubMed: 20506290
DOI: 10.1002/PRO.416

実験手法

X-RAY DIFFRACTION (2.35 Å)