2XA8
Crystal structure of the Fab domain of omalizumab at 2.41A
Summary for 2XA8
Entry DOI | 10.2210/pdb2xa8/pdb |
Descriptor | OMALIZUMAB HEAVY CHAIN, OMALIZUMAB LIGHT CHAIN (3 entities in total) |
Functional Keywords | xolair, allergy, immune system |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 47220.26 |
Authors | Huang, C.H.,Hung, F.H.A.,Lim, C.,Chang, T.W.,Ma, C. (deposition date: 2010-03-30, release date: 2011-05-11, Last modification date: 2023-12-20) |
Primary citation | Wright, J.D.,Chu, H.M.,Huang, C.H.,Ma, C.,Chang, T.W.,Lim, C. Structural and Physical Basis for Anti-IgE Therapy. Sci Rep, 5:11581-11581, 2015 Cited by PubMed: 26113483DOI: 10.1038/srep11581 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
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