2XA8

Crystal structure of the Fab domain of omalizumab at 2.41A

Summary for 2XA8

• Entry DOI: 10.2210/pdb2xa8/pdb
• Descriptor: OMALIZUMAB HEAVY CHAIN, OMALIZUMAB LIGHT CHAIN (3 entities in total)
• Functional Keywords: xolair, allergy, immune system
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 47220.26

Authors

Huang, C.H.,Hung, F.H.A.,Lim, C.,Chang, T.W.,Ma, C. (deposition date: 2010-03-30, release date: 2011-05-11, Last modification date: 2023-12-20)

• Primary citation: Wright, J.D.,Chu, H.M.,Huang, C.H.,Ma, C.,Chang, T.W.,Lim, C.; Structural and Physical Basis for Anti-IgE Therapy.; Sci Rep, 5:11581-11581, 2015; PubMed: 26113483; DOI: 10.1038/srep11581

Experimental method

X-RAY DIFFRACTION (2.42 Å)