2X97

Crystal structure of AnCE-RXP407 complex

2X97 の概要

• エントリーDOI: 10.2210/pdb2x97/pdb
• 関連するPDBエントリー: 1J36 1J37 1J38 2X8Y 2X8Z 2X90 2X91 2X92 2X93 2X94 2X95 2X96
• 関連するBIRD辞書のPRD_ID: PRD_001050
• 分子名称: ANGIOTENSIN CONVERTING ENZYME, beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N~2~-acetyl-N-{(1R)-1-[(S)-[(2S)-3-{[(2S)-1-amino-1-oxopropan-2-yl]amino}-2-methyl-3-oxopropyl](hydroxy)phosphoryl]-2-phenylethyl}-L-alpha-asparagine, ... (6 entities in total)
• 機能のキーワード: hydrolase, ace inhibitor, zinc metallopeptidase
• 由来する生物種: DROSOPHILA MELANOGASTER (FRUIT FLY)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 71231.86

構造登録者

Akif, M.,Georgiadis, D.,Mahajan, A.,Dive, V.,Sturrock, E.D.,Isaac, R.E.,Acharya, K.R. (登録日: 2010-03-14, 公開日: 2010-06-02, 最終更新日: 2020-07-29)

• 主引用文献: Akif, M.,Georgiadis, D.,Mahajan, A.,Dive, V.,Sturrock, E.D.,Isaac, R.E.,Acharya, K.R.; High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs.; J.Mol.Biol., 400:502-, 2010; PubMed: 20488190; DOI: 10.1016/J.JMB.2010.05.024

実験手法

X-RAY DIFFRACTION (1.85 Å)