2X57

Crystal structure of the extracellular domain of human Vasoactive intestinal polypeptide receptor 2

Summary for 2X57

DescriptorVASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 (2 entities in total)
Functional Keywordsg-protein coupled receptor, circadian rhythm, male reproduction, hormone binding, growth, receptor, transducer, class b gpcr, immune system
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCell membrane; Multi-pass membrane protein P41587
Total number of polymer chains3
Total molecular weight39792.67
Authors
Primary citation
Pike, A.C.W.,Barr, A.J.,Quigley, A.,Burgess Brown, N.,De Riso, A.,Bullock, A.,Berridge, G.,Muniz, J.R.C.,Chaikaud, A.,Vollmar, M.,Krojer, T.,Ugochukwu, E.,von Delft, F.,Edwards, A.,Arrowsmith, C.H.,Weigelt, J.,Bountra, C.,Carpenter, E.P.
Crystal Structure of the Extracellular Domain of Human Vasoactive Intestinal Polypeptide Receptor 2
To be Published,
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.243301.8%13.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution