2X1E
The crystal structure of mature acyl coenzyme A:isopenicillin N acyltransferase from Penicillium chrysogenum in complex 6- aminopenicillanic acid
Summary for 2X1E
Entry DOI | 10.2210/pdb2x1e/pdb |
Related | 2X1C 2X1D |
Descriptor | ACYL-COENZYME, PHOSPHATE ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | zymogen, transferase, ntn-hydrolase, penicillin biosynthesis, acyltransferase, antibiotic biosynthesis |
Biological source | PENICILLIUM CHRYSOGENUM |
Total number of polymer chains | 4 |
Total formula weight | 161274.22 |
Authors | Bokhove, M.,Yoshida, H.,Hensgens, C.M.H.,van der Laan, J.M.,Sutherland, J.D.,Dijkstra, B.W. (deposition date: 2009-12-23, release date: 2010-03-09, Last modification date: 2023-12-20) |
Primary citation | Bokhove, M.,Yoshida, H.,Hensgens, C.M.H.,Van Der Laan, J.M.,Sutherland, J.D.,Dijkstra, B.W. Structures of an Isopenicillin N Converting Ntn-Hydrolase Reveal Different Catalytic Roles for the Active Site Residues of Precursor and Mature Enzyme. Structure, 18:301-, 2010 Cited by PubMed: 20223213DOI: 10.1016/J.STR.2010.01.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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