2WV9
Crystal Structure of the NS3 protease-helicase from Murray Valley encephalitis virus
2WV9 の概要
エントリーDOI | 10.2210/pdb2wv9/pdb |
関連するPDBエントリー | 2V8O |
分子名称 | FLAVIVIRIN PROTEASE NS2B REGULATORY SUBUNIT, FLAVIVIRIN PROTEASE NS3 CATALYTIC SUBUNIT (2 entities in total) |
機能のキーワード | nucleotide-binding, capsid protein, rna replication, envelope protein, virion, helicase, hydrolase, flavivirus, nucleotidyltransferase |
由来する生物種 | MURRAY VALLEY ENCEPHALITIS VIRUS |
細胞内の位置 | Capsid protein C: Virion (Potential). Peptide pr: Secreted (By similarity). Small envelope protein M: Virion membrane; Multi-pass membrane protein (By similarity). Envelope protein E: Virion membrane; Multi- pass membrane protein (By similarity). Non-structural protein 1: Secreted. Non-structural protein 2A: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease subunit NS2B: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Non-structural protein 4A: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): P05769 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 74056.55 |
構造登録者 | Assenberg, R.,Mastrangelo, E.,Walter, T.S.,Verma, A.,Milani, M.,Owens, R.J.,Stuart, D.I.,Grimes, J.M.,Mancini, E.J. (登録日: 2009-10-15, 公開日: 2009-12-01, 最終更新日: 2023-12-20) |
主引用文献 | Assenberg, R.,Mastrangelo, E.,Walter, T.S.,Verma, A.,Milani, M.,Owens, R.J.,Stuart, D.I.,Grimes, J.M.,Mancini, E.J. Crystal Structure of a Novel Conformational State of the Flavivirus Ns3 Protein: Implications for Polyprotein Processing and Viral Replication. J.Virol., 83:12895-, 2009 Cited by PubMed: 19793813DOI: 10.1128/JVI.00942-09 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.75 Å) |
構造検証レポート
検証レポート(詳細版)
をダウンロード
![ダウンロード](/newweb/media/icons/dl.png)