2WUG

Crystal structure of S114A mutant of HsaD from Mycobacterium tuberculosis in complex with HOPDA

Summary for 2WUG

• Entry DOI: 10.2210/pdb2wug/pdb
• Related: 2VF2 2WUD 2WUE 2WUF
• Descriptor: 2-HYDROXY-6-OXO-6-PHENYLHEXA-2,4-DIENOATE HYDROLASE BPHD, (3E)-2,6-DIOXO-6-PHENYLHEX-3-ENOATE, THIOCYANATE ION, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Total number of polymer chains: 2
• Total formula weight: 64383.35

Authors

Lack, N.A.,Yam, K.C.,Lowe, E.D.,Horsman, G.P.,Owen, R.L.,Sim, E.,Eltis, L.D. (deposition date: 2009-10-02, release date: 2009-10-20, Last modification date: 2023-12-20)

• Primary citation: Lack, N.A.,Yam, K.C.,Lowe, E.D.,Horsman, G.P.,Owen, R.L.,Sim, E.,Eltis, L.D.; Characterization of a C-C Hydrolase from Mycobacterium Tuberuclosis Involved in Cholesterol Metabolism.; J.Biol.Chem., 285:434-, 2010; PubMed: 19875455; DOI: 10.1074/JBC.M109.058081

Experimental method

X-RAY DIFFRACTION (1.8 Å)