2WTZ

MurE ligase of Mycobacterium Tuberculosis

2WTZ の概要

• エントリーDOI: 10.2210/pdb2wtz/pdb
• 分子名称: UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE, URIDINE-5'-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE-D-GLUTAMATE, MAGNESIUM ION (3 entities in total)
• 機能のキーワード: nucleotide-binding, peptidoglycan synthesis, mure, ligase, cell shape, cell cycle, mycobacterium tuberculosis, cell wall biogenesis/degradation, atp-binding, peptidoglycan, cell division
• 由来する生物種: MYCOBACTERIUM TUBERCULOSIS
• 細胞内の位置: Cytoplasm (By similarity): P65477
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 225434.15

構造登録者

Basavannacharya, C.,Robertson, G.,Munshi, T.,Keep, N.H.,Bhakta, S. (登録日: 2009-09-25, 公開日: 2009-12-15, 最終更新日: 2023-12-20)

• 主引用文献: Basavannacharya, C.,Robertson, G.,Munshi, T.,Keep, N.H.,Bhakta, S.; ATP-Dependent Mure Ligase in Mycobacterium Tuberculosis: Biochemical and Structural Characterisation.; Tuberculosis(Edinb.), 90:16-, 2010; PubMed: 19945347; DOI: 10.1016/J.TUBE.2009.10.007

実験手法

X-RAY DIFFRACTION (3 Å)