2WM3

Crystal structure of NmrA-like family domain containing protein 1 in complex with niflumic acid

Summary for 2WM3

Related2EXX
DescriptorNMRA-LIKE FAMILY DOMAIN CONTAINING PROTEIN 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, ... (7 entities in total)
Functional Keywordsprotein binding
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm Q9HBL8
Total number of polymer chains1
Total molecular weight34893.65
Authors
Primary citation
Bhatia, C.,Yue, W.W.,Pilka, E.,Ugochukwu, E.,Savitsky, P.,Hozjan, V.,Roos, A.K.,Filippakopoulos, P.,von Delft, F.,Heightman, T.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U.
Crystal Structure of Nmra-Like Family Domain Containing Protein 1 in Complex with Niflumic Acid
To be Published,
Experimental method
X-RAY DIFFRACTION (1.85 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21160.7%0.8%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution