2WIG

NONAGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA4

2WIG の概要

• エントリーDOI: 10.2210/pdb2wig/pdb
• 関連するPDBエントリー: 1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW 2J4C 2WID 2WIF 2WIJ 2WIK
• 分子名称: CHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: aging, hydrolase, inhibition, polymorphism, glycoprotein, serine esterase, disease mutation
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62381.59

構造登録者

Carletti, E.,Aurbek, N.,Gillon, E.,Loiodice, M.,Nicolet, Y.,Fontecilla, J.,Masson, P.,Thiermann, H.,Nachon, F.,Worek, F. (登録日: 2009-05-11, 公開日: 2009-05-19, 最終更新日: 2023-12-13)

• 主引用文献: Carletti, E.,Aurbek, N.,Gillon, E.,Loiodice, M.,Nicolet, Y.,Fontecilla-Camps, J.C.,Masson, P.,Thiermann, H.,Nachon, F.,Worek, F.; Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.; Biochem. J., 421:97-106, 2009; PubMed: 19368529; DOI: 10.1042/BJ20090091

実験手法

X-RAY DIFFRACTION (2.15 Å)