2WFD

Structure of the human cytosolic leucyl-tRNA synthetase editing domain

2WFD の概要

分子名称LEUCYL-TRNA SYNTHETASE, CYTOPLASMIC (1 entity in total)
機能のキーワードaminoacyl-trna synthetase, phosphoprotein, editing domain, nucleotide-binding, hydrolysis of mis-charged trnas, protein biosynthesis, leucyl-trna synthetase, human, ligase, cytoplasm, atp-binding, polymorphism
由来する生物種HOMO SAPIENS (HUMAN)
細胞内の位置Cytoplasm (By similarity) Q9P2J5
ポリマー鎖数2
分子量合計56943.39
構造登録者
Seiradake, E.,Mao, W.,Hernandez, V.,Baker, S.J.,Plattner, J.J.,Alley, M.R.K.,Cusack, S. (登録日: 2009-04-03, 公開日: 2009-05-19, 最終更新日: 2011-07-13)
主引用文献
Seiradake, E.,Mao, W.,Hernandez, V.,Baker, S.J.,Plattner, J.J.,Alley, M.R.K.,Cusack, S.
Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles.
J.Mol.Biol., 390:196-, 2009
PubMed: 19426743 (主引用文献が同じPDBエントリー)
DOI: 10.1016/J.JMB.2009.04.073
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (3.25 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.246130.4%6.9%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード

他の静止画像(非対称単位)

Molmil generated image of 2wfd
回転なし
Molmil generated image of 2wfd
x軸(左右方向)周りに90°回転
Molmil generated image of 2wfd
y軸(上下方向)周りに90°回転