2WF5

Structure of Beta-Phosphoglucomutase inhibited with Glucose-6-phosphate and trifluoromagnesate

2WF5 の概要

• エントリーDOI: 10.2210/pdb2wf5/pdb
• 関連するPDBエントリー: 1LVH 1O03 1O08 1Z4N 1Z4O 1ZOL 2WF6 2WF7 2WF8 2WF9 2WFA 2WHE
• 分子名称: BETA-PHOSPHOGLUCOMUTASE, 6-O-phosphono-beta-D-glucopyranose, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: isomerase, phosphotransferase, magnesium fluoride, transition state analogue, haloacid dehalogenase superfamily
• 由来する生物種: LACTOCOCCUS LACTIS
• 細胞内の位置: Cytoplasm : P71447
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24629.64

構造登録者

Bowler, M.W.,Baxter, N.J.,Webster, C.E.,Hounslow, A.M.,Cliff, M.J.,Williams, N.H.,Hollfelder, F.,Gamblin, S.,Blackburn, G.M.,Waltho, J.P. (登録日: 2009-04-03, 公開日: 2009-09-15, 最終更新日: 2023-12-13)

• 主引用文献: Baxter, N.J.,Bowler, M.W.,Alizadeh, T.,Cliff, M.J.,Hounslow, A.M.,Wu, B.,Berkowitz, D.B.,Williams, N.H.,Blackburn, G.M.,Waltho, J.P.; Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.; Proc. Natl. Acad. Sci. U.S.A., 107:4555-4560, 2010; PubMed: 20164409; DOI: 10.1073/pnas.0910333106

実験手法

X-RAY DIFFRACTION (1.3 Å)