2WC3

Structure of family 1 beta-glucosidase from Thermotoga maritima in complex with 3-imino-2-oxa-(+)-8-epi-castanospermine

2WC3 の概要

• エントリーDOI: 10.2210/pdb2wc3/pdb
• 関連するPDBエントリー: 1OD0 1OIF 1OIM 1OIN 1UZ1 1W3J 2CBU 2CBV 2CES 2CET 2J75 2J77 2J78 2J79 2J7B 2J7C 2J7D 2J7E 2J7F 2J7G 2J7H 2JAL 2VRJ 2WBG 2WC4
• 分子名称: BETA-GLUCOSIDASE A, (3Z,5S,6R,7S,8S,8aR)-3-(octylimino)hexahydro[1,3]oxazolo[3,4-a]pyridine-5,6,7,8-tetrol (3 entities in total)
• 機能のキーワード: castanospermine, glycoside hydrolase, polysaccharide degradation, cellulose degradation, carbohydrate metabolism, family 1, hydrolase, inhibitors, glycosidase
• 由来する生物種: THERMOTOGA MARITIMA
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 217028.16

構造登録者

Aguilar, M.,Gloster, T.M.,Turkenburg, J.P.,Garcia-Moreno, M.I.,Ortiz Mellet, C.,Davies, G.J.,Garcia Fernandez, J.M. (登録日: 2009-03-08, 公開日: 2009-04-14, 最終更新日: 2023-12-13)

• 主引用文献: Aguilar-Moncayo, M.,Gloster, T.M.,Turkenburg, J.P.,Garcia-Moreno, M.I.,Ortiz Mellet, C.,Davies, G.J.,Garcia Fernandez, J.M.; Glycosidase Inhibition by Ring-Modified Castanospermine Analogues: Tackling Enzyme Selectivity by Inhibitor Tailoring.; Org.Biomol.Chem., 7:2738-, 2009; PubMed: 19532990; DOI: 10.1039/B906968B

実験手法

X-RAY DIFFRACTION (2 Å)