2WAX

Structure of the human DDX6 C-terminal domain in complex with an EDC3- FDF peptide

2WAX の概要

• エントリーDOI: 10.2210/pdb2wax/pdb
• 関連するPDBエントリー: 1VEC 2VC8 2WAY
• 分子名称: ATP-DEPENDENT RNA HELICASE DDX6, ENHANCER OF MRNA-DECAPPING PROTEIN 3, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ... (5 entities in total)
• 機能のキーワード: dead-box protein, nucleotide-binding, p54, rck, mirna, p-bodies, helicase, decapping, rna-binding, proto-oncogene, phosphoprotein, chromosomal rearrangement, atp-dependent rna helicase, hydrolase, cytoplasm, mrna decay, atp-binding
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Cytoplasm, P-body: P26196 2WAX
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 56797.96

構造登録者

Tritschler, F.,Weichenrieder, O. (登録日: 2009-02-18, 公開日: 2009-03-24, 最終更新日: 2023-12-13)

• 主引用文献: Tritschler, F.,Braun, J.E.,Eulalio, A.,Truffault, V.,Izaurralde, E.,Weichenrieder, O.; Structural Basis for the Mutually Exclusive Anchoring of P Body Components Edc3 and Tral to the Dead Box Protein Ddx6/Me31B.; Mol.Cell, 33:661-, 2009; PubMed: 19285948; DOI: 10.1016/J.MOLCEL.2009.02.014

実験手法

X-RAY DIFFRACTION (2.3 Å)