2W9D
Structure of Fab fragment of the ICSM 18 - anti-Prp therapeutic antibody at 1.57 A resolution.
Summary for 2W9D
Entry DOI | 10.2210/pdb2w9d/pdb |
Related | 2W9E |
Descriptor | ICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN, ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | immune system, prion, prp, fab |
Biological source | MUS MUSCULUS More |
Total number of polymer chains | 2 |
Total formula weight | 46573.72 |
Authors | Antonyuk, S.V.,Trevitt, C.R.,Strange, R.W.,Jackson, G.S.,Sangar, D.,Batchelor, M.,Jones, S.,Georgiou, T.,Cooper, S.,Fraser, C.,Khalili-Shirazi, A.,Clarke, A.R.,Hasnain, S.S.,Collinge, J. (deposition date: 2009-01-23, release date: 2009-02-03, Last modification date: 2023-12-13) |
Primary citation | Antonyuk, S.V.,Trevitt, C.R.,Strange, R.W.,Jackson, G.S.,Sangar, D.,Batchelor, M.,Cooper, S.,Fraser, C.,Jones, S.,Georgiou, T.,Khalili-Shirazi, A.,Clarke, A.R.,Hasnain, S.S.,Collinge, J. Crystal Structure of Human Prion Protein Bound to a Therapeutic Antibody. Proc.Natl.Acad.Sci.USA, 106:2554-, 2009 Cited by PubMed: 19204296DOI: 10.1073/PNAS.0809170106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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