2W8X

Structure of the tick ion-channel modulator Ra-KLP

Summary for 2W8X

• Entry DOI: 10.2210/pdb2w8x/pdb
• Descriptor: ION-CHANNEL MODULATOR RAKLP, GLYCEROL, ACETATE ION, ... (5 entities in total)
• Functional Keywords: salivary gland, kunitz domains, maxik channel activation, sulphur sad, membrane protein
• Biological source: RHIPICEPHALUS APPENDICULATUS (TICK)
• Total number of polymer chains: 2
• Total formula weight: 17058.89

Authors

Paesen, G.C.,Siebold, C.,Dallas, M.,Peers, C.,Harlos, K.,Nuttall, P.A.,Nunn, M.A.,Stuart, D.I.,Esnouf, R.M. (deposition date: 2009-01-20, release date: 2009-05-05, Last modification date: 2017-06-28)

• Primary citation: Paesen, G.C.,Siebold, C.,Dallas, M.L.,Peers, C.,Harlos, K.,Nuttall, P.A.,Nunn, M.A.,Stuart, D.I.,Esnouf, R.M.; An Ion-Channel Modulator from the Saliva of the Brown Ear Tick Has a Highly Modified Kunitz/Bpti Structure.; J.Mol.Biol., 389:734-, 2009; PubMed: 19394347; DOI: 10.1016/J.JMB.2009.04.045

Experimental method

X-RAY DIFFRACTION (1.6 Å)