2W4O

Crystal structure of Human CAMK4 in complex with 4-Amino(sulfamoyl- phenylamino)-triazole-carbothioic acid (2,6-difluoro-phenyl)-amide)

2W4O の概要

• エントリーDOI: 10.2210/pdb2w4o/pdb
• 分子名称: CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV, 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE (3 entities in total)
• 機能のキーワード: calmodulin-binding, nucleotide-binding, serine/threonine-protein kinase, atp-binding, phosphoprotein, kinase, nucleus, transferase
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Cytoplasm: Q16566
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39751.72

構造登録者

Muniz, J.R.C.,Rellos, P.,Gileadi, O.,Fedorov, O.,Filippakopoulos, P.,Salah, E.,Pike, A.,Phillips, C.,Niesen, F.,Shrestha, L.,Burgess-Brown, N.,Bullock, A.,Berridge, G.,von Delft, F.,Edwards, A.M.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Knapp, S. (登録日: 2008-11-28, 公開日: 2009-01-20, 最終更新日: 2024-02-07)

• 主引用文献: Muniz, J.R.C.,Rellos, P.,Gileadi, O.,Fedorov, O.,Filippakopoulos, P.,Salah, E.,Pike, A.,Phillips, C.,Niesen, F.,Shrestha, L.,Burgess-Brown, N.,Bullock, A.,Berridge, G.,von Delft, F.,Edwards, A.M.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Knapp, S.; Crystal Structure of Human Camk4 in Complex with 4-Amino(Sulfamoyl-Phenylamino)-Triazole- Carbothioic Acid (2,6-Difluoro-Phenyl)-Amide); To be Published,

実験手法

X-RAY DIFFRACTION (2.17 Å)