2W3H

Cyanide bound structure of the first GAF domain of Mycobacterium tuberculosis DosS

Summary for 2W3H

• Entry DOI: 10.2210/pdb2w3h/pdb
• Related: 2W3D 2W3E 2W3F 2W3G
• Descriptor: TWO COMPONENT SENSOR HISTIDINE KINASE DEVS (GAF FAMILY PROTEIN), PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ... (5 entities in total)
• Functional Keywords: redox sensor, mycobacterium tuberculosis, heme, kinase, hypoxia, gaf domain, transferase
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Cellular location: Cytoplasm (Probable): P95194
• Total number of polymer chains: 2
• Total formula weight: 34837.07

Authors

Kang, B.S.,Cho, H.Y.,Cho, H.J. (deposition date: 2008-11-12, release date: 2009-03-10, Last modification date: 2024-05-08)

• Primary citation: Cho, H.Y.,Cho, H.J.,Kim, Y.M.,Oh, J.I.,Kang, B.S.; Structural Insight Into the Heme-Based Redox Sensing by Doss from Mycobacterium Tuberculosis.; J.Biol.Chem., 284:13057-, 2009; PubMed: 19276084; DOI: 10.1074/JBC.M808905200

Experimental method

X-RAY DIFFRACTION (1.8 Å)