2W10

Mona SH3C in complex

Summary for 2W10

Related2D0N 1R1Q 1H3H 1R1S 1OEB 1UTI 1R1P
DescriptorGRB2-RELATED ADAPTOR PROTEIN 2, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23, PHOSPHATE ION, ... (4 entities in total)
Functional Keywordsalternative splicing, tpr repeat, sh2 domain, sh3 domain, coiled coil, protein phosphatase, cytoplasmic vesicle, phosphoprotein, signal tranduction, sh3 domain-complex, sh3, gads, mona, dimer, hd-ptp, hydrolase, cytoplasm
Biological sourceMUS MUSCULUS (MOUSE)
Cellular locationCytoplasmic vesicle (By similarity) Q6PB44
Total number of polymer chains4
Total molecular weight16939.03
Authors
Harkiolaki, M.,Feller, S.M. (deposition date: 2008-10-13, release date: 2009-05-19, Last modification date: 2011-07-13)
Primary citation
Harkiolaki, M.,Tsirka, T.,Lewitzky, M.,Simister, P.C.,Joshi, D.,Bird, L.E.,Jones, E.Y.,O'Reilly, N.,Feller, S.M.
Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17:809-, 2009
PubMed: 19523899 (PDB entries with the same primary citation)
DOI: 10.1016/J.STR.2009.03.017
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.238904.1%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution