2VXV

Crystal structure of human IgG ABT-325 Fab Fragment

Summary for 2VXV

• Entry DOI: 10.2210/pdb2vxv/pdb
• Related: 2VXT 2VXU
• Descriptor: HUMAN IGG ABT-325, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, ... (5 entities in total)
• Functional Keywords: immune system, il-18, fab, th1/th2 cells, autoimmunity
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 47779.32

Authors

Argiriadi, M.A.,Xiang, T.,Wu, C.,Ghayur, T.,Borhani, D.W. (deposition date: 2008-07-10, release date: 2009-06-23, Last modification date: 2023-12-13)

• Primary citation: Argiriadi, M.A.,Xiang, T.,Wu, C.,Ghayur, T.,Borhani, D.W.; Unusual Water-Mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18.; J.Biol.Chem., 284:24478-, 2009; PubMed: 19553661; DOI: 10.1074/JBC.M109.023887

Experimental method

X-RAY DIFFRACTION (1.49 Å)