2VOC

THIOREDOXIN A ACTIVE SITE MUTANTS FORM MIXED DISULFIDE DIMERS THAT RESEMBLE ENZYME-SUBSTRATE REACTION INTERMEDIATE

Summary for 2VOC

DescriptorTHIOREDOXIN, DI(HYDROXYETHYL)ETHER (3 entities in total)
Functional Keywordsthioredoxin, thioredoxin fold, electron transport, bacillus, homodimer, disulfide, transport, redox-active center
Biological sourceBacillus subtilis subsp. subtilis str. 168
Total number of polymer chains2
Total molecular weight25024.57
Authors
Kouwen, T.R.H.M.,Andrell, J.,Schrijver, R.,Dubois, J.Y.F.,Maher, M.J.,Iwata, S.,Carpenter, E.P.,van Dijl, J.M. (deposition date: 2008-02-13, release date: 2009-03-10, Last modification date: 2018-02-28)
Primary citation
Kouwen, T.R.,Andrell, J.,Schrijver, R.,Dubois, J.Y.,Maher, M.J.,Iwata, S.,Carpenter, E.P.,van Dijl, J.M.
Thioredoxin A active-site mutants form mixed disulfide dimers that resemble enzyme-substrate reaction intermediates.
J. Mol. Biol., 379:520-534, 2008
PubMed: 18455736 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2008.03.077
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.5 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2361401.1%5.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution