2VOC

THIOREDOXIN A ACTIVE SITE MUTANTS FORM MIXED DISULFIDE DIMERS THAT RESEMBLE ENZYME-SUBSTRATE REACTION INTERMEDIATE

2VOC の概要

• エントリーDOI: 10.2210/pdb2voc/pdb
• 分子名称: THIOREDOXIN, DI(HYDROXYETHYL)ETHER (3 entities in total)
• 機能のキーワード: thioredoxin, thioredoxin fold, electron transport, bacillus, homodimer, disulfide, transport, redox-active center
• 由来する生物種: Bacillus subtilis subsp. subtilis str. 168
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 25024.57

構造登録者

Kouwen, T.R.H.M.,Andrell, J.,Schrijver, R.,Dubois, J.Y.F.,Maher, M.J.,Iwata, S.,Carpenter, E.P.,van Dijl, J.M. (登録日: 2008-02-13, 公開日: 2009-03-10, 最終更新日: 2023-12-13)

• 主引用文献: Kouwen, T.R.,Andrell, J.,Schrijver, R.,Dubois, J.Y.,Maher, M.J.,Iwata, S.,Carpenter, E.P.,van Dijl, J.M.; Thioredoxin A active-site mutants form mixed disulfide dimers that resemble enzyme-substrate reaction intermediates.; J. Mol. Biol., 379:520-534, 2008; PubMed: 18455736; DOI: 10.1016/j.jmb.2008.03.077

実験手法

X-RAY DIFFRACTION (1.5 Å)