2VFJ

Structure of the A20 Ovarian Tumour (OTU) domain

2VFJ の概要

• エントリーDOI: 10.2210/pdb2vfj/pdb
• 分子名称: TUMOR NECROSIS FACTOR, SULFATE ION, MAGNESIUM ION (3 entities in total)
• 機能のキーワード: phosphorylation, cysteine protease, metal-binding, ovarian tumour, thiol protease, dna-binding, polymorphism, lys63-linked, hydrolase, cytoplasm, ubiquitin, zinc-finger, deubiquitinating enzyme, cytokine signalling, ubl conjugation pathway, otu, zinc, nf-kb, nucleus, protease, apoptosis
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Cytoplasm: P21580
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 172822.48

構造登録者

Komander, D.,Barford, D. (登録日: 2007-11-04, 公開日: 2007-12-04, 最終更新日: 2011-07-13)

• 主引用文献: Komander, D.,Barford, D.; Structure of the A20 Otu Domain and Mechanistic Insights Into Deubiquitination; Biochem.J., 409:77-, 2008; PubMed: 17961127; DOI: 10.1042/BJ20071399

実験手法

X-RAY DIFFRACTION (3.2 Å)