2VC5

Structural basis for natural lactonase and promiscuous phosphotriesterase activities

Summary for 2VC5

• Entry DOI: 10.2210/pdb2vc5/pdb
• Related: 2VC7
• Descriptor: ARYLDIALKYLPHOSPHATASE, FE (II) ION, COBALT (II) ION, ... (6 entities in total)
• Functional Keywords: phosphotriesterase, promiscuous activities, enzyme evolution, hyperthermophilic, lactonase, hydrolase, biotechnology, quorum sensing
• Biological source: SULFOLOBUS SOLFATARICUS
• Total number of polymer chains: 4
• Total formula weight: 144574.32

Authors

Elias, M.,Dupuy, J.,Merone, L.,Mandrich, L.,Moniot, S.,Lecomte, C.,Rossi, M.,Masson, P.,Manco, G.,Chabriere, E. (deposition date: 2007-09-18, release date: 2008-04-15, Last modification date: 2023-12-13)

• Primary citation: Elias, M.,Dupuy, J.,Merone, L.,Mandrich, L.,Porzio, E.,Moniot, S.,Rochu, D.,Lecomte, C.,Rossi, M.,Masson, P.,Manco, G.,Chabriere, E.; Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities.; J.Mol.Biol., 379:1017-, 2008; PubMed: 18486146; DOI: 10.1016/J.JMB.2008.04.022

Experimental method

X-RAY DIFFRACTION (2.6 Å)