2VB7

beta-ketoacyl-ACP synthase I (KAS) from E. coli, apo structure after soak in PEG solution

2VB7 の概要

• エントリーDOI: 10.2210/pdb2vb7/pdb
• 関連するPDBエントリー: 1DD8 1EK4 1F91 1FJ4 1FJ8 1G5X 1H4F 2AQ7 2AQB 2BUH 2BUI 2BYW 2BYX 2BYY 2BYZ 2BZ3 2BZ4 2VB8 2VB9 2VBA
• 分子名称: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1 (3 entities in total)
• 機能のキーワード: fatty acid biosynthesis, cytoplasm, antibiotic, transferase, acyltransferase, lipid synthesis, fatty acid synthesis
• 由来する生物種: ESCHERICHIA COLI; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 170656.81

構造登録者

Pappenberger, G.,Schulz-Gasch, T.,Bailly, J.,Hennig, M. (登録日: 2007-09-06, 公開日: 2007-12-25, 最終更新日: 2023-12-13)

• 主引用文献: Pappenberger, G.,Schulz-Gasch, T.,Kusznir, E.,Mueller, F.,Hennig, M.; Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis.; Acta Crystallogr.,Sect.D, 63:1208-, 2007; PubMed: 18084068; DOI: 10.1107/S0907444907049852

実験手法

X-RAY DIFFRACTION (1.6 Å)