2V7O

Crystal structure of human calcium-calmodulin-dependent protein kinase II gamma

Summary for 2V7O

Entry DOI	10.2210/pdb2v7o/pdb
Descriptor	CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II GAMMA CHAIN, BISINDOLYLMALEIMIDE IX, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	kinase, s/t kinase, transferase, atp-binding, serine/threonine-protein kinase, nucleotide-binding, phosphorylation, calmodulin-binding
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	39083.60
Authors	Pike, A.C.W.,Rellos, P.,Fedorov, O.,Burgess-Brown, N.,Shrestha, L.,Ugochukwu, E.,Pilka, E.S.,von Delft, F.,Edwards, A.,Weigelt, J.,Arrowsmith, C.H.,Sundstrom, M.,Knapp, S. (deposition date: 2007-07-31, release date: 2007-09-11, Last modification date: 2023-12-13)
Primary citation	Rellos, P.,Pike, A.C.W.,Niesen, F.H.,Salah, E.,Lee, W.H.,von Delft, F.,Knapp, S. Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation. Plos Biol., 8:426-, 2010 Cited by PubMed: 20668654 DOI: 10.1371/JOURNAL.PBIO.1000426 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation