2V7O

Crystal structure of human calcium-calmodulin-dependent protein kinase II gamma

2V7O の概要

• エントリーDOI: 10.2210/pdb2v7o/pdb
• 分子名称: CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II GAMMA CHAIN, BISINDOLYLMALEIMIDE IX, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: kinase, s/t kinase, transferase, atp-binding, serine/threonine-protein kinase, nucleotide-binding, phosphorylation, calmodulin-binding
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39083.60

構造登録者

Pike, A.C.W.,Rellos, P.,Fedorov, O.,Burgess-Brown, N.,Shrestha, L.,Ugochukwu, E.,Pilka, E.S.,von Delft, F.,Edwards, A.,Weigelt, J.,Arrowsmith, C.H.,Sundstrom, M.,Knapp, S. (登録日: 2007-07-31, 公開日: 2007-09-11, 最終更新日: 2023-12-13)

• 主引用文献: Rellos, P.,Pike, A.C.W.,Niesen, F.H.,Salah, E.,Lee, W.H.,von Delft, F.,Knapp, S.; Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation.; Plos Biol., 8:426-, 2010; PubMed: 20668654; DOI: 10.1371/JOURNAL.PBIO.1000426

実験手法

X-RAY DIFFRACTION (2.25 Å)