2V2F

Crystal structure of PBP1a from drug-resistant strain 5204 from Streptococcus pneumoniae

Summary for 2V2F

Entry DOI	10.2210/pdb2v2f/pdb
Descriptor	PENICILLIN BINDING PROTEIN 1A, BARIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total)
Functional Keywords	transpeptidase activity, peptidoglycan synthesis, transferase, hydrolase
Biological source	STREPTOCOCCUS PNEUMONIAE More
Total number of polymer chains	2
Total formula weight	46404.52
Authors	Job, V.,Carapito, R.,Vernet, T.,Dideberg, O.,Dessen, A.,Zapun, A. (deposition date: 2007-06-05, release date: 2007-12-25, Last modification date: 2023-12-13)
Primary citation	Job, V.,Carapito, R.,Vernet, T.,Dessen, A.,Zapun, A. Common Alterations in Pbp1A from Resistant Streptococcus Pneumoniae Decrease its Reactivity Toward {Beta}-Lactams: Structural Insights. J.Biol.Chem., 283:4886-, 2008 Cited by PubMed: 18055459 DOI: 10.1074/JBC.M706181200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation