2V1W

Crystal structure of human LIM protein RIL (PDLIM4) PDZ domain bound to the C-terminal peptide of human alpha-actinin-1

Summary for 2V1W

• Entry DOI: 10.2210/pdb2v1w/pdb
• Related: 2V1X
• Descriptor: PDZ AND LIM DOMAIN PROTEIN 4, 1,2-ETHANEDIOL, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: actin, stress, fibre dynamics, cytoskeleton, lim domain, metal-binding, phosphorylation, structural protein
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 19494.35

Authors

Soundararajan, M.,Shrestha, L.,Pike, A.C.W.,Salah, E.,Burgess-Brown, N.,Elkins, J.,Umeano, C.,Ugochukwu, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Weigelt, J.,Sundstrom, M.,Doyle, D. (deposition date: 2007-05-30, release date: 2007-06-12, Last modification date: 2023-12-13)

• Primary citation: Elkins, J.M.,Gileadi, C.,Shrestha, L.,Phillips, C.,Wang, J.,Muniz, J.R.C.,Doyle, D.A.; Unusual Binding Interactions in Pdz Domain Crystal Structures Help Explain Binding Mechanisms.; Protein Sci., 19:731-, 2010; PubMed: 20120020; DOI: 10.1002/PRO.349

Experimental method

X-RAY DIFFRACTION (1.9 Å)