2TYS

CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES

2TYS の概要

• エントリーDOI: 10.2210/pdb2tys/pdb
• 分子名称: TRYPTOPHAN SYNTHASE, SODIUM ION, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-L-TRYPTOPHANE, ... (5 entities in total)
• 機能のキーワード: lyase, carbon-oxygen lyase, tryptophan biosynthesis, pyridoxal phosphate
• 由来する生物種: Salmonella typhimurium; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72116.06

構造登録者

Rhee, S.,Parris, K.D.,Hyde, C.C.,Ahmed, S.A.,Miles, E.W.,Davies, D.R. (登録日: 1997-01-08, 公開日: 1997-04-01, 最終更新日: 2024-02-21)

• 主引用文献: Rhee, S.,Parris, K.D.,Hyde, C.C.,Ahmed, S.A.,Miles, E.W.,Davies, D.R.; Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.; Biochemistry, 36:7664-7680, 1997; PubMed: 9201907; DOI: 10.1021/bi9700429

実験手法

X-RAY DIFFRACTION (1.9 Å)