2TOH
TYROSINE HYDROXYLASE CATALYTIC AND TETRAMERIZATION DOMAINS FROM RAT
Summary for 2TOH
Entry DOI | 10.2210/pdb2toh/pdb |
Descriptor | TYROSINE 3-MONOOXYGENASE, FE (III) ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | hydroxylase, neurotransmitter biosynthesis, non-heme iron, pterin co-substrate, catecholamine biosynthesis, oxidoreductase |
Biological source | Rattus norvegicus (Norway rat) |
Total number of polymer chains | 1 |
Total formula weight | 39620.62 |
Authors | Goodwill, K.E.,Sabatier, C.,Stevens, R.C. (deposition date: 1998-08-26, release date: 1999-08-26, Last modification date: 2024-04-03) |
Primary citation | Goodwill, K.E.,Sabatier, C.,Stevens, R.C. Crystal structure of tyrosine hydroxylase with bound cofactor analogue and iron at 2.3 A resolution: self-hydroxylation of Phe300 and the pterin-binding site. Biochemistry, 37:13437-13445, 1998 Cited by PubMed: 9753429DOI: 10.1021/bi981462g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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