2TOH

TYROSINE HYDROXYLASE CATALYTIC AND TETRAMERIZATION DOMAINS FROM RAT

2TOH の概要

• エントリーDOI: 10.2210/pdb2toh/pdb
• 分子名称: TYROSINE 3-MONOOXYGENASE, FE (III) ION, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: hydroxylase, neurotransmitter biosynthesis, non-heme iron, pterin co-substrate, catecholamine biosynthesis, oxidoreductase
• 由来する生物種: Rattus norvegicus (Norway rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39620.62

構造登録者

Goodwill, K.E.,Sabatier, C.,Stevens, R.C. (登録日: 1998-08-26, 公開日: 1999-08-26, 最終更新日: 2024-04-03)

• 主引用文献: Goodwill, K.E.,Sabatier, C.,Stevens, R.C.; Crystal structure of tyrosine hydroxylase with bound cofactor analogue and iron at 2.3 A resolution: self-hydroxylation of Phe300 and the pterin-binding site.; Biochemistry, 37:13437-13445, 1998; PubMed: 9753429; DOI: 10.1021/bi981462g

実験手法

X-RAY DIFFRACTION (2.3 Å)