2TMN

CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN

2TMN の概要

• エントリーDOI: 10.2210/pdb2tmn/pdb
• 分子名称: Thermolysin, CALCIUM ION, ZINC ION, ... (5 entities in total)
• 機能のキーワード: hydrolase-hydrolase inhibitor complex, metalloproteinase, hydrolase/hydrolase inhibitor
• 由来する生物種: Bacillus thermoproteolyticus
• 細胞内の位置: Secreted: P00800
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34798.19

構造登録者

Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W. (登録日: 1987-06-29, 公開日: 1989-01-09, 最終更新日: 2022-11-23)

• 主引用文献: Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W.; Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin.; Eur.J.Biochem., 157:261-268, 1986; PubMed: 3709536; DOI: 10.1111/j.1432-1033.1986.tb09664.x

実験手法

X-RAY DIFFRACTION (1.6 Å)