2SGP
PRO 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
Summary for 2SGP
Entry DOI | 10.2210/pdb2sgp/pdb |
Descriptor | PROTEINASE B, OVOMUCOID INHIBITOR, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | complex (serine protease-inhibitor), serine proteinase, protein inhibitor, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Meleagris gallopavo (turkey) More |
Cellular location | Secreted: P68390 |
Total number of polymer chains | 2 |
Total formula weight | 24317.45 |
Authors | Huang, K.,Lu, W.,Anderson, S.,Laskowski Jr., M.,James, M.N.G. (deposition date: 1999-03-25, release date: 2001-01-31, Last modification date: 2023-08-30) |
Primary citation | Bateman, K.S.,Huang, K.,Anderson, S.,Lu, W.,Qasim, M.A.,Laskowski Jr., M.,James, M.N. Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I J.Mol.Biol., 305:839-849, 2001 Cited by PubMed: 11162096DOI: 10.1006/jmbi.2000.4343 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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