2SAK

STAPHYLOKINASE (SAKSTAR VARIANT)

2SAK の概要

• エントリーDOI: 10.2210/pdb2sak/pdb
• 分子名称: STAPHYLOKINASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
• 機能のキーワード: plasminogen activation, fibrinolysis, staphylokinase, hydrolase, plasminogen activator
• 由来する生物種: Staphylococcus aureus
• 細胞内の位置: Secreted: P68802
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14021.01

構造登録者

Rabijns, A.,De Bondt, H.L.,De Maeyer, M.,Lasters, I.,De Ranter, C. (登録日: 1997-02-20, 公開日: 1998-02-25, 最終更新日: 2024-02-21)

主引用文献

Rabijns, A.,De Bondt, H.L.,De Ranter, C.
Three-dimensional structure of staphylokinase, a plasminogen activator with therapeutic potential.
Nat.Struct.Biol., 4:357-360, 1997

PubMed Abstract: The three-dimensional structure of staphylokinase has been determined at 1.8 A. The puntative site of interaction with plasminogen was identified and epitopes were mapped.

PubMed: 9145104
DOI: 10.1038/nsb0597-357

実験手法

X-RAY DIFFRACTION (1.8 Å)