2RU1

Solution structure of esf3

2RU1 の概要

• エントリーDOI: 10.2210/pdb2ru1/pdb
• NMR情報: BMRB: 11540
• 分子名称: Uncharacterized protein (1 entity in total)
• 機能のキーワード: plant peptide hormone, hormone
• 由来する生物種: Arabidopsis thaliana (mouse-ear cress,thale-cress)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 7976.43

構造登録者

Umetsu, Y.,Mori, M.,Ohki, S. (登録日: 2013-11-06, 公開日: 2014-04-23, 最終更新日: 2024-10-16)

主引用文献

Costa, L.M.,Marshall, E.,Tesfaye, M.,Silverstein, K.A.,Mori, M.,Umetsu, Y.,Otterbach, S.L.,Papareddy, R.,Dickinson, H.G.,Boutiller, K.,Vandenbosch, K.A.,Ohki, S.,Gutierrez-marcos, J.F.
Central cell-derived peptides regulate early embryo patterning in flowering plants
Science, 344:168-172, 2014

PubMed Abstract: Plant embryogenesis initiates with the establishment of an apical-basal axis; however, the molecular mechanisms accompanying this early event remain unclear. Here, we show that a small cysteine-rich peptide family is required for formation of the zygotic basal cell lineage and proembryo patterning in Arabidopsis. EMBRYO SURROUNDING FACTOR 1 (ESF1) peptides accumulate before fertilization in central cell gametes and thereafter in embryo-surrounding endosperm cells. Biochemical and structural analyses revealed cleavage of ESF1 propeptides to form biologically active mature peptides. Further, these peptides act in a non-cell-autonomous manner and synergistically with the receptor-like kinase SHORT SUSPENSOR to promote suspensor elongation through the YODA mitogen-activated protein kinase pathway. Our findings demonstrate that the second female gamete and its sexually derived endosperm regulate early embryonic patterning in flowering plants.

PubMed: 24723605
DOI: 10.1126/science.1243005

実験手法

SOLUTION NMR