2RRA

Solution structure of RNA binding domain in human Tra2 beta protein in complex with RNA (GAAGAA)

Summary for 2RRA

• Entry DOI: 10.2210/pdb2rra/pdb
• Related: 2RRB
• Descriptor: cDNA FLJ40872 fis, clone TUTER2000283, highly similar to Homo sapiens transformer-2-beta (SFRS10) gene, 5'-R(*GP*AP*AP*GP*AP*A)-3' (2 entities in total)
• Functional Keywords: rrm domain, rbd, protein-rna complex, rna binding protein-rna complex, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, rna binding protein/rna
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 13075.59

Authors

Tsuda, K.,Kuwasako, K.,Takahashi, M.,Someya, T.,Inoue, M.,Kigawa, T.,Terada, T.,Shirouzu, M.,Sugano, S.,Muto, Y.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2010-06-17, release date: 2011-04-27, Last modification date: 2011-07-13)

• Primary citation: Tsuda, K.,Someya, T.,Kuwasako, K.,Takahashi, M.,He, F.,Unzai, S.,Inoue, M.,Harada, T.,Watanabe, S.,Terada, T.,Kobayashi, N.,Shirouzu, M.,Kigawa, T.,Tanaka, A.,Sugano, S.,Guntert, P.,Yokoyama, S.,Muto, Y.; Structural basis for the dual RNA-recognition modes of human Tra2-beta RRM.; Nucleic Acids Res., 39:1538-1553, 2011; PubMed: 20926394; DOI: 10.1093/nar/gkq854

Experimental method

SOLUTION NMR