2RQR
The solution structure of human DOCK2 SH3 domain - ELMO1 peptide chimera complex
Summary for 2RQR
Entry DOI | 10.2210/pdb2rqr/pdb |
Descriptor | Engulfment and cell motility protein 1,Dedicator of cytokinesis protein 2 (1 entity in total) |
Functional Keywords | kiaa0209, kiaa0281, apoptosis, membrane, phagocytosis, phosphoprotein, sh3-binding, cytoskeleton, guanine-nucleotide releasing factor, sh3 domain, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 12635.98 |
Authors | Yokoyama, S.,Tochio, N.,Koshiba, S.,Kigawa, T.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2009-10-21, release date: 2010-10-27, Last modification date: 2024-05-01) |
Primary citation | Hanawa-Suetsugu, K.,Kukimoto-Niino, M.,Mishima-Tsumagari, C.,Akasaka, R.,Ohsawa, N.,Sekine, S.,Ito, T.,Tochio, N.,Koshiba, S.,Kigawa, T.,Terada, T.,Shirouzu, M.,Nishikimi, A.,Uruno, T.,Katakai, T.,Kinashi, T.,Kohda, D.,Fukui, Y.,Yokoyama, S. Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms. Proc.Natl.Acad.Sci.USA, 109:3305-3310, 2012 Cited by PubMed: 22331897DOI: 10.1073/pnas.1113512109 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report