2RPN

A crucial role for high intrinsic specificity in the function of yeast SH3 domains

2RPN の概要

• エントリーDOI: 10.2210/pdb2rpn/pdb
• 分子名称: Actin-binding protein, Actin-regulating kinase 1 (2 entities in total)
• 機能のキーワード: sh3 domain, extended peptide, 3-10 helix, acetylation, actin-binding, cytoplasm, cytoskeleton, phosphoprotein, structural protein
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast); 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton, actin patch: P15891 P53974
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8721.61

構造登録者

Stollar, E.J.,Garcia, B.,Chong, A.,Forman-Kay, J.,Davidson, A. (登録日: 2008-06-12, 公開日: 2009-06-16, 最終更新日: 2024-05-29)

• 主引用文献: Stollar, E.J.,Garcia, B.,Chong, P.A.,Rath, A.,Lin, H.,Forman-Kay, J.D.,Davidson, A.R.; Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p; J.Biol.Chem., 284:26918-26927, 2009; PubMed: 19590096; DOI: 10.1074/jbc.M109.028431

実験手法

SOLUTION NMR