2RNY

Complex Structures of CBP Bromodomain with H4 ack20 Peptide

2RNY の概要

• エントリーDOI: 10.2210/pdb2rny/pdb
• 分子名称: CREB-binding protein, Histone H4 (2 entities in total)
• 機能のキーワード: bromodomain, histone, creb, cbp, p53, acetylation, activator, chromosomal rearrangement, disease mutation, host-virus interaction, metal-binding, methylation, nucleus, phosphoprotein, transcription, transcription regulation, transferase, zinc, zinc-finger, chromosomal protein, dna-binding, nucleosome core, transferase-nuclear protein complex, transferase/nuclear protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: Q92793; Nucleus: P62805
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 16213.63

構造登録者

Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Zhou, M.M. (登録日: 2008-02-03, 公開日: 2008-05-06, 最終更新日: 2023-11-15)

• 主引用文献: Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Moshkina, N.,Zhou, M.M.; Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300; Structure, 16:643-652, 2008; PubMed: 18400184; DOI: 10.1016/j.str.2008.01.010

実験手法

SOLUTION NMR