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2RMX

Solution structure of the SHP-1 C-terminal SH2 domain complexed with a tyrosine-phosphorylated peptide from NKG2A

2RMX の概要
エントリーDOI10.2210/pdb2rmx/pdb
分子名称Tyrosine-protein phosphatase non-receptor type 6, NKG2-A/NKG2-B type II integral membrane protein (2 entities in total)
機能のキーワードsh2 domain, protein-peptide complex, phosphorylated peptide recognition, phosphotyrosine binding domain, signal transduction, alternative splicing, cytoplasm, hydrolase, nucleus, phosphoprotein, protein phosphatase, glycoprotein, lectin, membrane, receptor, signal-anchor, transmembrane, signaling protein, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
由来する生物種Homo sapiens (Human)
詳細
細胞内の位置Cytoplasm: P29350
Membrane; Single-pass type II membrane protein: P26715
タンパク質・核酸の鎖数2
化学式量合計14364.83
構造登録者
Kasai, T.,Koshiba, S.,Inoue, M.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2007-11-30, 公開日: 2008-12-02, 最終更新日: 2022-03-16)
主引用文献Koshiba, S.,Kasai, T.,Sato, M.,Tomizawa, T.,Motoda, Y.,Tochio, N.,Kobayashi, N.,Harada, T.,Inoue, M.,Tanaka, A.,Kigawa, T.,Yokoyama, S.
Structural basis for the recognition of the two NKG2A immunoreceptor tyrosine-based inhibitory motifs (ITIMs) by the C-terminal SH2 domain of protein tyrosine phosphatase SHP-1
To be Published,
実験手法
SOLUTION NMR
構造検証レポート
Validation report summary of 2rmx
検証レポート(詳細版)ダウンロードをダウンロード

217705

件を2024-03-27に公開中

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