2RMX
Solution structure of the SHP-1 C-terminal SH2 domain complexed with a tyrosine-phosphorylated peptide from NKG2A
2RMX の概要
エントリーDOI | 10.2210/pdb2rmx/pdb |
分子名称 | Tyrosine-protein phosphatase non-receptor type 6, NKG2-A/NKG2-B type II integral membrane protein (2 entities in total) |
機能のキーワード | sh2 domain, protein-peptide complex, phosphorylated peptide recognition, phosphotyrosine binding domain, signal transduction, alternative splicing, cytoplasm, hydrolase, nucleus, phosphoprotein, protein phosphatase, glycoprotein, lectin, membrane, receptor, signal-anchor, transmembrane, signaling protein, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi |
由来する生物種 | Homo sapiens (Human) 詳細 |
細胞内の位置 | Cytoplasm: P29350 Membrane; Single-pass type II membrane protein: P26715 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 14364.83 |
構造登録者 | Kasai, T.,Koshiba, S.,Inoue, M.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2007-11-30, 公開日: 2008-12-02, 最終更新日: 2022-03-16) |
主引用文献 | Koshiba, S.,Kasai, T.,Sato, M.,Tomizawa, T.,Motoda, Y.,Tochio, N.,Kobayashi, N.,Harada, T.,Inoue, M.,Tanaka, A.,Kigawa, T.,Yokoyama, S. Structural basis for the recognition of the two NKG2A immunoreceptor tyrosine-based inhibitory motifs (ITIMs) by the C-terminal SH2 domain of protein tyrosine phosphatase SHP-1 To be Published, |
実験手法 | SOLUTION NMR |
構造検証レポート
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