2RK8

The Structure of rat cytosolic PEPCK in complex with phosphonoformate

2RK8 の概要

• エントリーDOI: 10.2210/pdb2rk8/pdb
• 関連するPDBエントリー: 2RK7 2RKA 2RKD 2RKE
• 分子名称: Phosphoenolpyruvate carboxykinase, cytosolic [GTP], MANGANESE (II) ION, SODIUM ION, ... (7 entities in total)
• 機能のキーワード: kinase, gluconeogenesis, lyase, decarboxylase, gtp-binding, nucleotide-binding
• 由来する生物種: Rattus norvegicus (Norway rat)
• 細胞内の位置: Cytoplasm: P07379
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 139893.61

構造登録者

Sullivan, S.M.,Stiffin, R.M.,Carlson, G.M.,Holyoak, T. (登録日: 2007-10-16, 公開日: 2008-01-29, 最終更新日: 2024-02-21)

• 主引用文献: Stiffin, R.M.,Sullivan, S.M.,Carlson, G.M.,Holyoak, T.; Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.; Biochemistry, 47:2099-2109, 2008; PubMed: 18197707; DOI: 10.1021/bi7020662

実験手法

X-RAY DIFFRACTION (2 Å)