2RIG

CRYSTAL STRUCTURE OF RECOMBINANT RABBIT INTERFERON-GAMMA AT 2.7-ANGSTROMS RESOLUTION

Replaces:  1RIG

Summary for 2RIG

• Entry DOI: 10.2210/pdb2rig/pdb
• Descriptor: INTERFERON-GAMMA (1 entity in total)
• Functional Keywords: cytokine
• Biological source: Oryctolagus cuniculus (rabbit)
• Cellular location: Secreted: P30123
• Total number of polymer chains: 1
• Total formula weight: 16950.39

Authors

Samudzi, C.T.,Burton, L.E.,Rubin, J.R. (deposition date: 1993-01-11, release date: 1993-01-15, Last modification date: 2024-02-21)

Primary citation

Samudzi, C.T.,Burton, L.E.,Rubin, J.R.
Crystal structure of recombinant rabbit interferon-gamma at 2.7-A resolution.
J.Biol.Chem., 266:21791-21797, 1991

PubMed Abstract: The crystal structure of recombinant rabbit interferon-gamma was solved by the multiple isomorphous replacement technique at 2.7-A resolution and refined to a crystallographic R-factor of 26.2%. The interferon crystallizes with one-half of the functional dimer in the asymmetric unit, with the two polypeptide chains of the dimer related by a crystallographic 2-fold symmetry axis. The structure is predominantly alpha-helical with extensive interdigitation of the alpha-helical segments of the two polypeptide chains.

PubMed: 1939201

Experimental method

X-RAY DIFFRACTION (2.3 Å)