2RIG

CRYSTAL STRUCTURE OF RECOMBINANT RABBIT INTERFERON-GAMMA AT 2.7-ANGSTROMS RESOLUTION

「1RIG」から置き換えられました

2RIG の概要

• エントリーDOI: 10.2210/pdb2rig/pdb
• 分子名称: INTERFERON-GAMMA (1 entity in total)
• 機能のキーワード: cytokine
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• 細胞内の位置: Secreted: P30123
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16950.39

構造登録者

Samudzi, C.T.,Burton, L.E.,Rubin, J.R. (登録日: 1993-01-11, 公開日: 1993-01-15, 最終更新日: 2024-02-21)

主引用文献

Samudzi, C.T.,Burton, L.E.,Rubin, J.R.
Crystal structure of recombinant rabbit interferon-gamma at 2.7-A resolution.
J.Biol.Chem., 266:21791-21797, 1991

PubMed Abstract: The crystal structure of recombinant rabbit interferon-gamma was solved by the multiple isomorphous replacement technique at 2.7-A resolution and refined to a crystallographic R-factor of 26.2%. The interferon crystallizes with one-half of the functional dimer in the asymmetric unit, with the two polypeptide chains of the dimer related by a crystallographic 2-fold symmetry axis. The structure is predominantly alpha-helical with extensive interdigitation of the alpha-helical segments of the two polypeptide chains.

PubMed: 1939201

実験手法

X-RAY DIFFRACTION (2.3 Å)