2RFI
Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide
Summary for 2RFI
Entry DOI | 10.2210/pdb2rfi/pdb |
Related | 2IGQ |
Descriptor | Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, Histone H3, ZINC ION, ... (5 entities in total) |
Functional Keywords | euchromatic histone methyltransferase 1, structural genomics, structural genomics consortium, sgc, alternative splicing, ank repeat, chromatin regulator, nucleus, phosphorylation, polymorphism, s-adenosyl-l-methionine, acetylation, chromosomal protein, dna damage, dna repair, dna-binding, methylation, nucleosome core, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9H9B1 |
Total number of polymer chains | 4 |
Total formula weight | 69281.16 |
Authors | Min, J.,Wu, H.,Loppnau, P.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Plotnikov, A.N.,Structural Genomics Consortium (SGC) (deposition date: 2007-09-30, release date: 2007-10-23, Last modification date: 2023-08-30) |
Primary citation | Wu, H.,Min, J.,Lunin, V.V.,Antoshenko, T.,Dombrovski, L.,Zeng, H.,Allali-Hassani, A.,Campagna-Slater, V.,Vedadi, M.,Arrowsmith, C.H.,Plotnikov, A.N.,Schapira, M. Structural biology of human H3K9 methyltransferases Plos One, 5:e8570-e8570, 2010 Cited by PubMed: 20084102DOI: 10.1371/journal.pone.0008570 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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