2RFI

Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide

2RFI の概要

関連するPDBエントリー2IGQ
分子名称Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, Histone H3, ZINC ION, ... (5 entities in total)
機能のキーワードeuchromatic histone methyltransferase 1, structural genomics, structural genomics consortium, sgc, alternative splicing, ank repeat, chromatin regulator, nucleus, phosphorylation, polymorphism, s-adenosyl-l-methionine, acetylation, chromosomal protein, dna damage, dna repair, dna-binding, methylation, nucleosome core, transferase
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Nucleus Q9H9B1
ポリマー鎖数4
分子量合計69281.16
構造登録者
主引用文献
Wu, H.,Min, J.,Lunin, V.V.,Antoshenko, T.,Dombrovski, L.,Zeng, H.,Allali-Hassani, A.,Campagna-Slater, V.,Vedadi, M.,Arrowsmith, C.H.,Plotnikov, A.N.,Schapira, M.
Structural biology of human H3K9 methyltransferases
Plos One, 5:e8570-e8570, 2010
PubMed: 20084102 (主引用文献が同じPDBエントリー)
DOI: 10.1371/journal.pone.0008570
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.59 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.218401.1%8.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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