2REY

Crystal structure of the PDZ domain of human dishevelled 2 (homologous to Drosophila dsh)

2REY の概要

• エントリーDOI: 10.2210/pdb2rey/pdb
• 関連するPDBエントリー: 1L6O
• 分子名称: Segment polarity protein dishevelled homolog DVL-2 (2 entities in total)
• 機能のキーワード: pdz, bound peptide, peptide binding site, structural genomics, structural genomics consortium, sgc, developmental protein, phosphorylation, wnt signaling pathway, gene regulation
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : O14641
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 10822.40

構造登録者

Papagrigoriou, E.,Gileadi, C.,Elkins, J.,Cooper, C.,Ugochukwu, E.,Turnbull, A.,Pike, A.C.W.,Gileadi, O.,von Delft, F.,Sundstrom, M.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Doyle, D.,Structural Genomics Consortium (SGC) (登録日: 2007-09-27, 公開日: 2007-10-23, 最終更新日: 2023-08-30)

• 主引用文献: Papagrigoriou, E.,Gileadi, C.,Elkins, J.,Cooper, C.,Ugochukwu, E.,Turnbull, A.,Pike, A.C.W.,Gileadi, O.,von Delft, F.,Sundstrom, M.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Doyle, D.; Crystal structure of the PDZ domains of human dishevelled 2 (homologous to Drosophila dsh).; To be Published,

実験手法

X-RAY DIFFRACTION (1.55 Å)