2R99

Crystal structure of cyclophilin ABH-like domain of human peptidylprolyl isomerase E isoform 1

Replaces:  1ZCX

Summary for 2R99

• Entry DOI: 10.2210/pdb2r99/pdb
• Descriptor: Peptidyl-prolyl cis-trans isomerase E (2 entities in total)
• Functional Keywords: cis-trans isomerization, structural genomics consortium, sgc, alternative splicing, isomerase, mrna processing, mrna splicing, nucleus, rna-binding, rotamase, spliceosome
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q9UNP9
• Total number of polymer chains: 1
• Total formula weight: 18985.67

Authors

Walker, J.R.,Davis, T.,Newman, E.M.,Mackenzie, F.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-09-12, release date: 2007-09-25, Last modification date: 2023-08-30)

• Primary citation: Davis, T.L.,Walker, J.R.,Campagna-Slater, V.,Finerty, P.J.,Paramanathan, R.,Bernstein, G.,MacKenzie, F.,Tempel, W.,Ouyang, H.,Lee, W.H.,Eisenmesser, E.Z.,Dhe-Paganon, S.; Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.; PLoS Biol., 8:e1000439-e1000439, 2010; PubMed: 20676357; DOI: 10.1371/journal.pbio.1000439

Experimental method

X-RAY DIFFRACTION (1.61 Å)