2R83

Crystal structure analysis of human synaptotagmin 1 C2A-C2B

Summary for 2R83

• Entry DOI: 10.2210/pdb2r83/pdb
• Descriptor: Synaptotagmin-1, CHLORIDE ION (3 entities in total)
• Functional Keywords: c2a-c2b, exocytosis, calcium, cell junction, cytoplasmic vesicle, glycoprotein, lipoprotein, membrane, metal-binding, palmitate, phosphorylation, synapse, transmembrane, endocytosis-exocytosis complex, endocytosis
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein : P21579
• Total number of polymer chains: 2
• Total formula weight: 65352.56

Authors

Sutton, R.B.,Fuson, K.L.,Montes, M.,Robert, J.J. (deposition date: 2007-09-10, release date: 2008-02-12, Last modification date: 2023-08-30)

• Primary citation: Fuson, K.L.,Montes, M.,Robert, J.J.,Sutton, R.B.; Structure of human synaptotagmin 1 C2AB in the absence of Ca2+ reveals a novel domain association.; Biochemistry, 46:13041-13048, 2007; PubMed: 17956130; DOI: 10.1021/bi701651k

Experimental method

X-RAY DIFFRACTION (2.7 Å)